STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Snov_0450KEGG: azc:AZC_1773 putative methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase. (618 aa)    
Predicted Functional Partners:
Snov_0449
TIGRFAM: methylmalonyl-CoA mutase, large subunit; KEGG: azc:AZC_1772 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
 
0.996
Snov_1847
TIGRFAM: methylmalonyl-CoA epimerase; KEGG: xau:Xaut_4617 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.972
Snov_2773
PFAM: cobalamin B12-binding domain protein; KEGG: xau:Xaut_5018 cobalamin B12-binding domain-containing protein.
 
 0.935
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.911
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.909
Snov_0473
PFAM: AMP-dependent synthetase and ligase; KEGG: met:M446_6034 malonyl-CoA synthase.
     
 0.902
Snov_1580
PFAM: AMP-dependent synthetase and ligase; KEGG: xau:Xaut_0518 malonyl-CoA synthase.
     
 0.902
Snov_0452
PFAM: carboxyl transferase; KEGG: azc:AZC_1775 propionyl-CoA carboxylase.
 
   
 0.864
Snov_1616
TIGRFAM: succinate CoA transferase; KEGG: azc:AZC_3728 acetyl-CoA hydrolase; PFAM: acetyl-CoA hydrolase/transferase.
 
  
 0.853
Snov_0651
KEGG: azc:AZC_1535 arginine/ornithine transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein.
 
  
 0.844
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.