STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Snov_1601KEGG: acr:Acry_1270 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (367 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.985
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 0.979
Snov_0327
KEGG: xau:Xaut_1489 acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.
  
 0.960
Snov_0326
KEGG: azc:AZC_2376 acetolactate synthase large subunit; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding.
 
 0.926
Snov_0571
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; KEGG: mrd:Mrad2831_2117 thiamine pyrophosphate protein; Belongs to the TPP enzyme family.
 
 0.926
Snov_1602
TIGRFAM: tartrate dehydrogenase; KEGG: mno:Mnod_1445 tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase.
 
    
0.826
Snov_1600
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bbe:BBR47_25270 hypothetical protein.
   
   0.766
Snov_1599
Membrane protein AbrB duplication; KEGG: reh:H16_A3721 putative ammonia monooxygenase; TIGRFAM: membrane protein AbrB duplication; PFAM: putative ammonia monooxygenase.
       0.755
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.696
Snov_1529
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpd:RPD_2099 hypothetical protein.
  
 
 0.690
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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