STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)    
Predicted Functional Partners:
Snov_1825
TIGRFAM: citrate synthase I; KEGG: xau:Xaut_4425 citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.970
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.958
Snov_0482
KEGG: rpc:RPC_1050 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.942
Snov_2737
KEGG: bja:bll0226 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.942
Snov_1669
PFAM: Aldehyde Dehydrogenase; KEGG: atc:AGR_L_1402 probable aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.933
Snov_2051
KEGG: bja:bll7607 putative aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.933
Snov_2415
KEGG: mlo:mll6639 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.933
Snov_3467
KEGG: azc:AZC_4119 methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase.
  
 0.933
Snov_4280
KEGG: bbt:BBta_1974 NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.933
Snov_1616
TIGRFAM: succinate CoA transferase; KEGG: azc:AZC_3728 acetyl-CoA hydrolase; PFAM: acetyl-CoA hydrolase/transferase.
  
 0.931
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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