node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dsui_0019 | Dsui_1577 | Dsui_0019 | Dsui_1577 | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.913 |
Dsui_0019 | Dsui_2001 | Dsui_0019 | Dsui_2001 | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.941 |
Dsui_0019 | Dsui_2216 | Dsui_0019 | Dsui_2216 | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | 0.973 |
Dsui_0019 | Dsui_2217 | Dsui_0019 | Dsui_2217 | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component. | 0.424 |
Dsui_0019 | Dsui_2347 | Dsui_0019 | Dsui_2347 | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.511 |
Dsui_0019 | acsA | Dsui_0019 | Dsui_2003 | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.962 |
Dsui_0019 | mdh | Dsui_0019 | Dsui_2209 | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.946 |
Dsui_0019 | sucC | Dsui_0019 | Dsui_1445 | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.835 |
Dsui_1577 | Dsui_0019 | Dsui_1577 | Dsui_0019 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | 0.913 |
Dsui_1577 | Dsui_2001 | Dsui_1577 | Dsui_2001 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.435 |
Dsui_1577 | Dsui_2205 | Dsui_1577 | Dsui_2205 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | 0.438 |
Dsui_1577 | Dsui_2214 | Dsui_1577 | Dsui_2214 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.682 |
Dsui_1577 | Dsui_2216 | Dsui_1577 | Dsui_2216 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | 0.974 |
Dsui_1577 | Dsui_2217 | Dsui_1577 | Dsui_2217 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component. | 0.980 |
Dsui_1577 | acsA | Dsui_1577 | Dsui_2003 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.907 |
Dsui_1577 | mdh | Dsui_1577 | Dsui_2209 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.502 |
Dsui_1577 | sucC | Dsui_1577 | Dsui_1445 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.967 |
Dsui_2001 | Dsui_0019 | Dsui_2001 | Dsui_0019 | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. | 0.941 |
Dsui_2001 | Dsui_1577 | Dsui_2001 | Dsui_1577 | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.435 |
Dsui_2001 | Dsui_2205 | Dsui_2001 | Dsui_2205 | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | 0.860 |