STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srot_0470PFAM: DNA polymerase III delta; KEGG: rha:RHA1_ro01286 DNA polymerase III delta subunit. (333 aa)    
Predicted Functional Partners:
Srot_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.999
Srot_0234
SMART: AAA ATPase; KEGG: nfa:nfa3680 DNA polymerase III subunit delta'.
  
 
 0.999
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.999
Srot_1432
TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mab:MAB_2696c DNA polymerase III subunit alpha; SMART: phosphoesterase PHP domain protein.
  
 0.999
Srot_1012
KEGG: rha:RHA1_ro01291 ComEC operon protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
    
 0.820
Srot_0010
KEGG: rop:ROP_34640 hypothetical membrane protein; TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein.
  
  
 0.800
Srot_0469
PFAM: AMP-dependent synthetase and ligase; KEGG: rop:ROP_64530 putative acid--CoA ligase.
       0.773
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.771
Srot_0004
PFAM: protein of unknown function DUF721; KEGG: rer:RER_00050 hypothetical protein.
 
   
 0.765
Srot_2140
KEGG: mkm:Mkms_1431 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Protein of unknown function DUF2342.
  
     0.753
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.