STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srot_0484Aquaporin; KEGG: rsa:RSal33209_1492 aquaporin; Belongs to the MIP/aquaporin (TC 1.A.8) family. (303 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.738
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
     
 0.673
Srot_0759
PFAM: FAD dependent oxidoreductase; KEGG: mgi:Mflv_4821 FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.639
Srot_0482
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rha:RHA1_ro05061 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.604
Srot_0483
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: nfa:nfa9280 putative acyl-CoA dehydrogenase.
       0.576
Srot_0481
PFAM: MaoC domain protein dehydratase; KEGG: mab:MAB_2949c hypothetical protein.
   
   0.556
Srot_1112
KEGG: rer:RER_04800 CRP/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp.
   
 0.530
Srot_1792
KEGG: nml:Namu_5204 hypothetical protein.
   
 0.530
Srot_0480
PFAM: Polyketide cyclase/dehydrase; KEGG: mab:MAB_2950c hypothetical protein.
       0.511
Srot_0375
PFAM: Protein phosphatase 2C-like; KEGG: rop:ROP_35150 serine/threonine protein phosphatase PstP; SMART: protein phosphatase 2C domain protein.
    
   0.493
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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