STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srot_0600PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro02011 O-succinylbenzoic acid--CoA ligase. (391 aa)    
Predicted Functional Partners:
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
  
 0.985
menC
Mandelate racemase/muconate lactonizing protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
  0.970
Srot_0601
KEGG: rer:RER_16880 hypothetical protein.
       0.794
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
  
 0.786
Srot_2690
PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro05693 acyl-CoA synthetase.
  
     0.702
Srot_0603
PFAM: phosphate transporter; KEGG: rer:RER_36310 inorganic phosphate transporter.
  
    0.680
Srot_1345
Amino acid adenylation domain protein; KEGG: sma:SAV_3642 non-ribosomal peptide synthetase; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding.
 
   0.667
Srot_1351
PFAM: AMP-dependent synthetase and ligase; KEGG: app:CAP2UW1_3910 AMP-dependent synthetase and ligase.
  
     0.655
menA
1,4-dihydroxy-2-naphthoateoctaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.652
Srot_2767
PFAM: Beta-ketoacyl synthase; phosphopantetheine- binding; Acyl transferase; Thioesterase; KEGG: rha:RHA1_ro04065 polyketide synthase.
 
 0.602
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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