node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Srot_0682 | Srot_2618 | Srot_0682 | Srot_2618 | KEGG: mav:MAV_1509 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | KEGG: rha:RHA1_ro04291 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.992 |
Srot_0682 | dapA | Srot_0682 | Srot_1989 | KEGG: mav:MAV_1509 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.950 |
Srot_0682 | dapB | Srot_0682 | Srot_1995 | KEGG: mav:MAV_1509 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.626 |
Srot_0682 | lysA | Srot_0682 | Srot_0681 | KEGG: mav:MAV_1509 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.932 |
Srot_0682 | thrB | Srot_0682 | Srot_0684 | KEGG: mav:MAV_1509 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
Srot_0776 | Srot_1256 | Srot_0776 | Srot_1256 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. | 0.968 |
Srot_0776 | Srot_2443 | Srot_0776 | Srot_2443 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | 0.905 |
Srot_0776 | dapA | Srot_0776 | Srot_1989 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.469 |
Srot_0776 | dapB | Srot_0776 | Srot_1995 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.529 |
Srot_0776 | dapF | Srot_0776 | Srot_0947 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.943 |
Srot_0776 | lysA | Srot_0776 | Srot_0681 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.958 |
Srot_0776 | murE | Srot_0776 | Srot_2587 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.902 |
Srot_1256 | Srot_0776 | Srot_1256 | Srot_0776 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | 0.968 |
Srot_1256 | Srot_2443 | Srot_1256 | Srot_2443 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. | 0.962 |
Srot_1256 | Srot_2618 | Srot_1256 | Srot_2618 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. | KEGG: rha:RHA1_ro04291 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.666 |
Srot_1256 | dapA | Srot_1256 | Srot_1989 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.849 |
Srot_1256 | dapB | Srot_1256 | Srot_1995 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.859 |
Srot_1256 | dapF | Srot_1256 | Srot_0947 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.975 |
Srot_1256 | lysA | Srot_1256 | Srot_0681 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.927 |
Srot_1256 | murE | Srot_1256 | Srot_2587 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.902 |