STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (341 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.999
Srot_1128
KEGG: rop:ROP_07830 adenosylmethionine-8-amino-7- oxononanoate aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.998
Srot_0704
KEGG: rha:RHA1_ro01054 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II.
  
 0.979
Srot_2979
KEGG: mva:Mvan_1722 biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein.
  
 
 0.973
Srot_0707
KEGG: gbr:Gbro_2971 hypothetical protein.
 
  
 0.890
Srot_2022
PFAM: aminotransferase class-III; KEGG: rha:RHA1_ro05386 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.887
Srot_2408
8-amino-7-oxononanoate synthase; KEGG: rop:ROP_22760 putative aminotransferase; PFAM: aminotransferase class I and II.
  
 0.828
Srot_1583
PFAM: aminotransferase class-III; KEGG: mab:MAB_1703 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.640
Srot_0703
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: nml:Namu_3960 pyridoxamine 5'-phosphate oxidase-related FMN-binding.
       0.570
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
      
 0.515
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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