STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srot_0804Hypothetical protein; KEGG: cli:Clim_1716 STE24 endopeptidase. (102 aa)    
Predicted Functional Partners:
Srot_0320
PFAM: Aldehyde Dehydrogenase; KEGG: rha:RHA1_ro03944 succinic semialdehyde dehydrogenase.
     
  0.900
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
  0.900
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
     
  0.900
Srot_2154
KEGG: mab:MAB_3673 succinate dehydrogenase (cytochrome b-556 subunit) SdhC; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit.
     
  0.900
Srot_2155
KEGG: mjl:Mjls_1255 succinate dehydrogenase subunit D.
     
  0.900
Srot_2156
KEGG: rha:RHA1_ro06246 succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
     
  0.900
Srot_2157
KEGG: rop:ROP_63040 succinate dehydrogenase iron- sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
     
  0.900
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
  0.900
Srot_1230
PFAM: aminotransferase class I and II; KEGG: nfa:nfa54270 aminotransferase AlaT.
     
  0.800
argH
KEGG: mmi:MMAR_2469 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
     
  0.800
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.