STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srot_1545PFAM: isocitrate lyase and phosphorylmutase; KEGG: shw:Sputw3181_3788 isocitrate lyase family protein. (280 aa)    
Predicted Functional Partners:
Srot_2884
TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: rer:RER_50290 2-methylcitrate synthase/citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 0.911
Srot_2424
2-methylcitrate dehydratase; KEGG: cgb:cg2796 MmgE/PrpD family protein; PFAM: MmgE/PrpD family protein.
 
  
 0.881
Srot_2885
KEGG: rop:ROP_30470 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein.
 
  
 0.821
Srot_1546
PFAM: metallophosphoesterase; KEGG: rha:RHA1_ro06649 metallophosphoesterase.
       0.701
Srot_1547
PFAM: 4'-phosphopantetheinyl transferase; KEGG: rha:RHA1_ro06650 phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
       0.701
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.701
Srot_0185
TIGRFAM: citrate synthase I; KEGG: rha:RHA1_ro04998 type II citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.687
Srot_2451
PFAM: protein of unknown function DUF453; KEGG: pna:Pnap_3805 hypothetical protein.
 
  
 0.506
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
  
 0.444
Srot_1118
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
  
 0.435
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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