STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srot_1578Dihydropyrimidinase; KEGG: bcv:Bcav_2578 dihydropyrimidinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. (472 aa)    
Predicted Functional Partners:
Srot_2913
TIGRFAM: amidase, hydantoinase/carbamoylase family; KEGG: aau:AAur_0749 putative N-carbamoyl-L-amino acid amidohydrolase; PFAM: peptidase M20.
 
 
 0.940
pyrB
TIGRFAM: aspartate carbamoyltransferase; KEGG: rer:RER_30000 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.939
Srot_2484
TIGRFAM: amidase, hydantoinase/carbamoylase family; KEGG: rop:ROP_25390 peptidase M20 family protein; PFAM: peptidase M20.
 
 
 0.932
Srot_1579
5,10-methylenetetrahydromethanopterin reductase; KEGG: kra:Krad_4268 luciferase family protein; PFAM: Luciferase-like, subgroup.
 
     0.915
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
 
 0.821
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
       0.778
Srot_2158
KEGG: nml:Namu_0261 xanthine permease; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase.
  
  
 0.775
carB
KEGG: nfa:nfa36190 carbamoyl phosphate synthase large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family.
 
 
 0.764
carA
TIGRFAM: carbamoyl-phosphate synthase, small subunit; KEGG: mav:MAV_3390 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family.
 
  
 0.753
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.739
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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