STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (512 aa)    
Predicted Functional Partners:
Srot_1902
KEGG: nfa:nfa13180 putative aminopeptidase; TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase.
   
 0.918
Srot_0608
Gamma-glutamyltransferase; KEGG: mab:MAB_2788 gamma-glutamyltranspeptidase (GgtB); PFAM: gamma-glutamyltranspeptidase.
     
 0.911
Srot_0825
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.822
Srot_0302
KEGG: rer:RER_10910 cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.820
Srot_2440
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ami:Amir_4781 pyridoxal-5'-phosphate- dependent protein beta subunit.
    
 0.820
Srot_2032
PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: msm:MSMEG_2394 cystathionine gamma-lyase.
   
 
  0.800
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
    0.697
Srot_2097
KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein.
  
  
 0.672
Srot_2821
PFAM: glycoside hydrolase family 3 domain protein; KEGG: rer:RER_11170 glycosidase.
    
 0.612
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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