STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srot_2140KEGG: mkm:Mkms_1431 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Protein of unknown function DUF2342. (424 aa)    
Predicted Functional Partners:
Srot_1195
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.
  
  
 0.862
Srot_0470
PFAM: DNA polymerase III delta; KEGG: rha:RHA1_ro01286 DNA polymerase III delta subunit.
  
     0.753
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.748
Srot_0965
KEGG: gbr:Gbro_2249 hypothetical protein.
  
     0.732
clpP
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.726
Srot_2237
KEGG: msm:MSMEG_4287 integral membrane protein.
  
     0.718
Srot_0826
KEGG: mab:MAB_4410c PEP phosphonomutase and related enzymes.
   
    0.696
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
     0.659
Srot_2553
KEGG: gbr:Gbro_0943 hypothetical protein.
  
     0.655
Srot_2139
PDZ/DHR/GLGF domain protein; KEGG: rer:RER_22290 hypothetical protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein.
       0.651
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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