STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srot_2196KEGG: rer:RER_21890 two-component histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. (512 aa)    
Predicted Functional Partners:
Srot_2814
Response regulator receiver and ANTAR domain protein; KEGG: nfa:nfa18700 putative two-component system response regulator; PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver.
 
   
 0.896
Srot_2198
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: rop:ROP_64020 RNA polymerase ECF-type sigma factor SigH; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2.
     
 0.606
Srot_2197
TIGRFAM: anti-sigma factor; KEGG: mpa:MAP3323c hypothetical protein.
       0.597
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.585
whiB-2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.580
whiB-3
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.454
Srot_2270
SMART: regulatory protein MerR; KEGG: rop:ROP_06380 putative MerR family transcriptional regulator.
  
     0.451
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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