STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADG15501.1KEGG: bpy:Bphyt_1858 DNA ligase D; TIGRFAM: DNA ligase D; DNA polymerase LigD, ligase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. (937 aa)    
Predicted Functional Partners:
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.982
ku-2
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.954
ADG14116.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.952
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.928
ADG18032.1
KEGG: bpy:Bphyt_5444 DNA topoisomerase.
 
 
 
 0.821
ADG17919.1
KEGG: bxe:Bxe_B1314 putative exonuclease involved in mRNA processing.
 
 
 0.778
ADG18290.1
PFAM: protein of unknown function DUF72; KEGG: bpy:Bphyt_4684 protein of unknown function DUF72.
 
    0.740
ADG17329.1
PFAM: protein of unknown function DUF72; KEGG: bpy:Bphyt_2348 protein of unknown function DUF72.
 
    0.738
ADG18310.1
PFAM: DNA polymerase B region; DNA polymerase B exonuclease; KEGG: bpy:Bphyt_4655 DNA polymerase II; SMART: DNA-directed DNA polymerase B.
   
 0.725
ADG15561.1
KEGG: bxe:Bxe_A2262 DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.
   
 0.713
Your Current Organism:
Paraburkholderia sp. CCGE1002
NCBI taxonomy Id: 640511
Other names: P. sp. CCGE1002
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