node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADG16062.1 | folE | BC1002_2001 | BC1002_4574 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | TIGRFAM: GTP cyclohydrolase I; KEGG: bpy:Bphyt_4310 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. | 0.804 |
ADG16062.1 | folE2 | BC1002_2001 | BC1002_5273 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
ADG16062.1 | moaA | BC1002_2001 | BC1002_2155 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.809 |
ADG16062.1 | ndk | BC1002_2001 | BC1002_1856 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.917 |
ADG16062.1 | ribA | BC1002_2001 | BC1002_3780 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.813 |
ADG16062.1 | ribB | BC1002_2001 | BC1002_2321 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.845 |
ADG16367.1 | ADG16368.1 | BC1002_2309 | BC1002_2310 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: riboflavin synthase, alpha subunit; KEGG: bpy:Bphyt_3100 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 0.999 |
ADG16367.1 | folE | BC1002_2309 | BC1002_4574 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: GTP cyclohydrolase I; KEGG: bpy:Bphyt_4310 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. | 0.563 |
ADG16367.1 | moaA | BC1002_2309 | BC1002_2155 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.531 |
ADG16367.1 | ndk | BC1002_2309 | BC1002_1856 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.546 |
ADG16367.1 | ribA | BC1002_2309 | BC1002_3780 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.998 |
ADG16367.1 | ribB | BC1002_2309 | BC1002_2321 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
ADG16367.1 | ribB-2 | BC1002_2309 | BC1002_2592 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.992 |
ADG16367.1 | ribH | BC1002_2309 | BC1002_2322 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.991 |
ADG16368.1 | ADG16367.1 | BC1002_2310 | BC1002_2309 | TIGRFAM: riboflavin synthase, alpha subunit; KEGG: bpy:Bphyt_3100 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
ADG16368.1 | ribA | BC1002_2310 | BC1002_3780 | TIGRFAM: riboflavin synthase, alpha subunit; KEGG: bpy:Bphyt_3100 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.989 |
ADG16368.1 | ribB | BC1002_2310 | BC1002_2321 | TIGRFAM: riboflavin synthase, alpha subunit; KEGG: bpy:Bphyt_3100 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.995 |
ADG16368.1 | ribB-2 | BC1002_2310 | BC1002_2592 | TIGRFAM: riboflavin synthase, alpha subunit; KEGG: bpy:Bphyt_3100 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.995 |
ADG16368.1 | ribH | BC1002_2310 | BC1002_2322 | TIGRFAM: riboflavin synthase, alpha subunit; KEGG: bpy:Bphyt_3100 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.998 |
folE | ADG16062.1 | BC1002_4574 | BC1002_2001 | TIGRFAM: GTP cyclohydrolase I; KEGG: bpy:Bphyt_4310 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.804 |