Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureCTIGRFAM: urease, alpha subunit; KEGG: bpy:Bphyt_0928 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain-containing protein. (568 aa)    
Predicted Functional Partners:
ureB
TIGRFAM: urease, beta subunit; KEGG: bpy:Bphyt_0929 urease, beta subunit; PFAM: Urease beta subunit; Belongs to the urease beta subunit family.
 0.999
ureA
TIGRFAM: urease, gamma subunit; KEGG: bmj:BMULJ_00748 urease subunit gamma; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family.
 0.999
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.996
ureE
UreE urease accessory domain-containing protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.987
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.977
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.976
alc
TIGRFAM: allantoicase; KEGG: bxe:Bxe_A1928 allantoicase; PFAM: Allantoicase domain; Belongs to the allantoicase family.
    
  0.910
allA
Ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
    
  0.902
ADN60587.1
Ureidoglycolate lyase; KEGG: bpy:Bphyt_6912 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase.
   
 
  0.900
ADN56799.1
Urea ABC transporter, ATP-binding protein UrtD; KEGG: bxe:Bxe_A3686 branched chain amino acid ABC transporter ATPase; TIGRFAM: urea ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter related.
 
   
 0.641
Your Current Organism:
Burkholderia sp. CCGE1003
NCBI taxonomy Id: 640512
Other names: B. sp. CCGE1003
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