Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
recCExodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (1125 aa)    
Predicted Functional Partners:
recB
Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]
 
 0.999
recD
Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]
 
 0.998
ADN57976.1
PFAM: Class I peptide chain release factor; KEGG: bpy:Bphyt_1617 peptidyl-tRNA hydrolase domain protein.
       0.795
ADN59468.1
KEGG: bpy:Bphyt_3985 hypothetical protein.
  
   
 0.645
ADN57980.1
KEGG: bpy:Bphyt_1612 protein of unknown function DUF893 YccS/YhfK.
 
     0.637
ADN59256.1
PFAM: GumN family protein; KEGG: bxe:Bxe_A0187 hypothetical protein.
  
     0.511
ADN58105.1
Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: bpy:Bphyt_1569 putative signal transduction protein.
  
     0.463
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
  
 0.443
ADN57776.1
KEGG: bpy:Bphyt_2135 putative chaperone protein, HscA/DnaK.
  
   
 0.430
ADN59451.1
Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain-containing protein; helix-turn-helix- domain containing protein AraC type; methylguanine DNA methyltransferase ribonuclease domain protein; KEGG: transcriptional regulator, AraC family; SMART: Helix-turn-helix, AraC domain.
     
 0.424
Your Current Organism:
Burkholderia sp. CCGE1003
NCBI taxonomy Id: 640512
Other names: B. sp. CCGE1003
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