Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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gene co-occurrence
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ibpBSmall heat shock protein ibpB; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent. (142 aa)    
Predicted Functional Partners:
AEN62766.1
KEGG: enc:ECL_00015 heat shock protein; HAMAP: Small heat shock protein ibpA; PFAM: Heat shock protein Hsp20.
 
 
0.973
hspQ
Heat shock protein hspQ; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
   
  
 0.862
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
      
 0.857
malT
ATP-dependent transcriptional regulator, MalT-like, LuxR family; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
    
   0.772
hslR
RNA-binding S4 domain protein; KEGG: enc:ECL_04763 ribosome-associated heat shock protein HSP15; PFAM: RNA-binding S4; SMART: RNA-binding S4; Belongs to the HSP15 family.
   
  
 0.748
nhaA
Na(+)/H(+) antiporter nhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
      
 0.741
clpV1_5
TIGRFAM: ATPase, type VI secretion system, ClpV1; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: pam:PANA_4145 ClpV; SMART: ATPase, AAA+ type, core.
  
 
 0.732
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.732
AEN66561.1
TIGRFAM: ATPase, type VI secretion system, ClpV1; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp ATPase, C-terminal; KEGG: aha:AHA_1841 ClpA/ClpB family protein; SMART: ATPase, AAA+ type, core.
  
 
 0.732
clpA
TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: enc:ECL_02767 ATP-dependent Clp protease ATP-binding subunit; SMART: ATPase, AAA+ type, core; Belongs to the ClpA/ClpB family.
  
 
 0.718
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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