STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysC_2KEGG: enc:ECL_00276 aspartate kinase III; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT. (449 aa)    
Predicted Functional Partners:
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.988
asd_1
KEGG: enc:ECL_04795 aspartate-semialdehyde dehydrogenase Asd; TIGRFAM: Aspartate-semialdehyde dehydrogenase, proteobacteria; PFAM: Semialdehyde dehydrogenase, dimerisation region; Semialdehyde dehydrogenase, NAD-binding.
  
 
 0.948
usg_2
PFAM: Semialdehyde dehydrogenase, dimerisation region; Semialdehyde dehydrogenase, NAD-binding; KEGG: enc:ECL_03668 aspartate-semialdehyde dehydrogenase.
 
 
 0.925
metL_1
Aspartate kinase; KEGG: enc:ECL_05038 bifunctional aspartate kinase II/homoserine dehydrogenase II; TIGRFAM: Aspartate kinase region; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Aspartate/homoserine dehydrogenase, NAD-binding.
 
0.907
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 0.906
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.900
aspC_1
PFAM: Aminotransferase, class I/II; KEGG: enc:ECL_02725 aromatic amino acid aminotransferase.
  
 
 0.871
asnB_1
KEGG: enc:ECL_03041 asparagine synthetase B; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II.
 
 
 0.850
thrC
KEGG: enc:ECL_00816 threonine synthase; TIGRFAM: Threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.
 
 
 0.824
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
 
 0.814
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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