Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kamALysine-2,3-aminomutase-related protein; KEGG: enc:ECL_00546 L-lysine 2,3-aminomutase; TIGRFAM: lysine-2,3-aminomutase-related protein; Protein of unknown function DUF160; PFAM: Radical SAM. (342 aa)    
Predicted Functional Partners:
yjeA
Uncharacterized protein YjeA; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
 
  
 0.916
efp
Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.
 
   
 0.906
AEN65318.1
MCP methyltransferase, CheR-type; KEGG: enc:ECL_01414 chemotaxis methyltransferase CheR; PFAM: MCP methyltransferase, CheR-type; SMART: MCP methyltransferase, CheR-type.
    
   0.816
yfcM
PFAM: Protein of unknown function DUF462; KEGG: enc:ECL_03675 hypothetical protein.
  
   
 0.706
ygeA
Aspartate racemase; KEGG: enc:ECL_04167 putative racemase; TIGRFAM: Aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; Belongs to the aspartate/glutamate racemases family.
  
  
  0.689
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.677
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
  
 0.676
alr_1
TIGRFAM: Alanine racemase; HAMAP: Alanine racemase; KEGG: ent:Ent638_0257 alanine racemase; PFAM: Alanine racemase, N-terminal; Alanine racemase, C-terminal.
    
  0.593
dadX
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
  0.593
trpR
Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
  
    0.560
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.