Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (155 aa)    
Predicted Functional Partners:
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
 
 
 0.973
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.947
rnhB
Ribonuclease HII/HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.919
ssb
KEGG: enc:ECL_00317 single-strand DNA-binding protein ssb; TIGRFAM: Single-strand DNA-binding; PFAM: Primosome PriB/single-strand DNA-binding.
 
 
 0.848
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.758
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
      0.670
ygdG
HAMAP: Uncharacterized exonuclease xni; PFAM: 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; KEGG: enc:ECL_04131 exonuclease IX; SMART: 5'-3' exonuclease, N-terminal; Helix-hairpin-helix motif, class 2.
  
 0.644
sbcD_1
KEGG: enc:ECL_01153 exonuclease subunit SbcD; TIGRFAM: Exonuclease SbcD; PFAM: Metallophosphoesterase.
      
 0.611
dnaX_4
TIGRFAM: DNA polymerase III, subunit gamma/ tau; PFAM: ATPase, AAA-type, core; KEGG: enc:ECL_01241 DNA polymerase III subunits gamma and tau; SMART: ATPase, AAA+ type, core.
   
 0.603
holA
KEGG: enc:ECL_03056 DNA polymerase III subunit delta; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta.
     
 0.581
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.