Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
phoQ_2KEGG: enc:ECL_02505 sensor protein PhoQ; PFAM: PhoQ Sensor; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region. (487 aa)    
Predicted Functional Partners:
phoP_2
Two component transcriptional regulator, winged helix family; KEGG: ent:Ent638_1643 DNA-binding transcriptional regulator PhoP; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region.
 0.999
arcB_6
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response regulator, receiver region; Signal transduction h [...]
 
 0.967
barA_5
KEGG: enc:ECL_04118 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; Signal transduction response regulator, receiver region; Signal transduction hi [...]
  
 0.957
basR_2
Two component transcriptional regulator, winged helix family; KEGG: enc:ECL_04562 DNA-binding transcriptional regulator BasR; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region.
 0.853
phoB_1
Two component transcriptional regulator PhoB, winged helix family; TIGRFAM: Signal transduction response regulator, phosphate regulon transcriptional regulatory protein phoB; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; KEGG: enc:ECL_01154 transcriptional regulator PhoB; SMART: Signal transduction response regulator, receiver region.
 
 0.785
walR
Two component transcriptional regulator, winged helix family; KEGG: ctu:Ctu_41130 DNA-binding transcriptional regulator CpxR; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal.
 
 0.776
rstA
Two component transcriptional regulator, winged helix family; KEGG: enc:ECL_02269 DNA-binding transcriptional regulator RstA; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region.
 
 0.768
phoP_1
Two component transcriptional regulator, winged helix family; KEGG: cko:CKO_02246 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region.
 
 0.747
yicH
AsmA family protein; PFAM: AsmA; KEGG: enc:ECL_00105 hypothetical protein.
  
     0.741
baeR_2
Two component transcriptional regulator, winged helix family; KEGG: enc:ECL_03406 DNA-binding transcriptional regulator BaeR; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region.
 
 0.738
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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