Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
narL_2Two component transcriptional regulator, LuxR family; KEGG: enc:ECL_01619 nitrate/nitrite response regulator; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal. (216 aa)    
Predicted Functional Partners:
narX_1
Integral membrane sensor signal transduction histidine kinase; KEGG: enc:ECL_01620 nitrate/nitrite sensor protein NarX; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; HAMP linker domain.
 
 0.999
narQ
Integral membrane sensor signal transduction histidine kinase; KEGG: enc:ECL_03766 nitrate/nitrite sensor protein NarQ; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region; SMART: ATP-binding region, ATPase-like; HAMP linker domain.
 
 0.994
barA_5
KEGG: enc:ECL_04118 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; Signal transduction response regulator, receiver region; Signal transduction hi [...]
  
 0.990
arcB_6
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response regulator, receiver region; Signal transduction h [...]
  
 0.928
rpoA
SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type; TIGRFAM: DNA-directed RNA polymerase, alpha subunit; KEGG: rah:Rahaq_0367 DNA-directed RNA polymerase, subunit alpha; HAMAP: DNA-directed RNA polymerase, alpha subunit; PFAM: DNA-directed RNA polymerase, insert; DNA-directed RNA polymerase, dimerisation; RNA polymerase, alpha subunit, C-terminal.
    
   0.843
degS_2
KEGG: enc:ECL_00037 sensory histidine kinase UhpB; PFAM: MASE1; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like.
 
 0.776
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.752
rpoC_2
SMART: RNA polymerase, N-terminal; TIGRFAM: DNA-directed RNA polymerase, subunit beta-prime; KEGG: enc:ECL_00246 DNA-directed RNA polymerase subunit beta'; HAMAP: DNA-directed RNA polymerase subunit beta'; PFAM: RNA polymerase Rpb1, domain 1; RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5.
    
 
 0.750
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.749
rcsD_2
Hpt sensor signal transduction histidine kinase; KEGG: ent:Ent638_2796 phosphotransfer intermediate protein in two-component regulatory system with RcsBC; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like.
   
 0.655
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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