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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppk_1Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). (686 aa)    
Predicted Functional Partners:
ppx
KEGG: ent:Ent638_2991 exopolyphosphatase; TIGRFAM: exopolyphosphatase; PFAM: Ppx/GppA phosphatase; Belongs to the GppA/Ppx family.
 
  
 0.969
AEN64950.1
Polyphosphate kinase 2; KEGG: enc:ECL_01906 hypothetical protein; TIGRFAM: polyphosphate kinase 2; PFAM: Polyphosphate kinase 2.
 
  
 0.920
gppA
Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
 
  
 0.839
ppa
KEGG: enc:ECL_00630 inorganic pyrophosphatase; HAMAP: Inorganic pyrophosphatase; PFAM: Inorganic pyrophosphatase.
     
 0.768
AEN64939.1
KEGG: ent:Ent638_2049 inorganic diphosphatase; HAMAP: Inorganic pyrophosphatase; PFAM: Inorganic pyrophosphatase.
     
 0.768
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: enc:ECL_03791 phosphoribosylaminoimidazole synthetase; TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein.
     
 0.580
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.579
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
       0.552
pitA_1
PFAM: Phosphate transporter; Domain of unknown function, Spy-related; KEGG: enc:ECL_04911 phosphate transporter.
     
 0.537
pstS_3
KEGG: enc:ECL_05153 phosphate transport system substrate-binding protein; TIGRFAM: Periplasmic phosphate binding protein; PFAM: Bacterial extracellular solute-binding, family 1.
     
 0.537
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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