Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppxKEGG: ent:Ent638_2991 exopolyphosphatase; TIGRFAM: exopolyphosphatase; PFAM: Ppx/GppA phosphatase; Belongs to the GppA/Ppx family. (515 aa)    
Predicted Functional Partners:
ppk_1
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
 
  
 0.957
relA_2
(p)ppGpp synthetase I, SpoT/RelA; KEGG: enc:ECL_04116 GDP/GTP pyrophosphokinase; TIGRFAM: RelA/SpoT protein; PFAM: RelA/SpoT; TGS; Amino acid-binding ACT.
  
 
 0.955
spoT_2
(p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT protein; PFAM: RelA/SpoT; Metal-dependent phosphohydrolase, HD region, subdomain; TGS; KEGG: ent:Ent638_0089 bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region.
  
 
 0.952
gppA
Ppx/GppA phosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
  
  
 
0.951
ppa
KEGG: enc:ECL_00630 inorganic pyrophosphatase; HAMAP: Inorganic pyrophosphatase; PFAM: Inorganic pyrophosphatase.
      
 0.671
ubiC
Chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
  
   
 0.663
amtB
KEGG: enc:ECL_01212 ammonium transporter; TIGRFAM: Ammonium transporter; PFAM: Ammonium transporter.
      
 0.653
symE
PFAM: Protein of unknown function DUF1813, HSP20-like; KEGG: enc:ECL_04077 hypothetical protein.
      
 0.636
grxA
Glutaredoxin, GrxA family; KEGG: enc:ECL_02823 glutaredoxin 1; TIGRFAM: Glutaredoxin, GrxA; PFAM: Glutaredoxin.
     
 0.632
cheV
Response regulator receiver modulated CheW protein; KEGG: enc:ECL_03619 putative chemotaxis signal trancription protein; PFAM: CheW-like protein; Signal transduction response regulator, receiver region; SMART: CheW-like protein; Signal transduction response regulator, receiver region.
     
 0.629
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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