Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
yfgF_2KEGG: enc:ECL_03795 diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; MASE1; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted. (746 aa)    
Predicted Functional Partners:
arcB_6
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: enc:ECL_04591 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response regulator, receiver region; Signal transduction h [...]
  
 0.986
barA_5
KEGG: enc:ECL_04118 hybrid sensory histidine kinase BarA; PFAM: Protein of unknown function DUF2222; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; Signal transduction response regulator, receiver region; Signal transduction hi [...]
  
 
 0.976
ydaM_1
Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate cyclase, predicted; PAS fold-4; KEGG: enc:ECL_01825 diguanylate cyclase with PAS/PAC sensor; SMART: Diguanylate cyclase, predicted; PAS.
 
 0.948
AEN63054.1
Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate cyclase, predicted; KEGG: ent:Ent638_0264 diguanylate cyclase with PAS/PAC sensor; SMART: Diguanylate cyclase, predicted.
 
 0.935
yeaP_1
Diguanylate cyclase with GAF sensor; TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; GAF; KEGG: ent:Ent638_1659 diguanylate cyclase with GAF sensor; SMART: Diguanylate cyclase, predicted; GAF.
 
 
 0.900
cheV
Response regulator receiver modulated CheW protein; KEGG: enc:ECL_03619 putative chemotaxis signal trancription protein; PFAM: CheW-like protein; Signal transduction response regulator, receiver region; SMART: CheW-like protein; Signal transduction response regulator, receiver region.
  
 
 0.856
aer_3
Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor; TIGRFAM: PAS; PFAM: Chemotaxis methyl-accepting receptor, signalling; PAS fold-3; HAMP linker domain; KEGG: enc:ECL_04457 methyl-accepting chemotaxis sensory transducer; SMART: Chemotaxis methyl-accepting receptor, signalling; PAC motif.
  
 0.851
yfiN
SMART: Diguanylate cyclase, predicted; manually curated; TIGRFAM: Diguanylate cyclase, predicted; KEGG: enc:ECL_03935 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; HAMP linker domain.
  
 
 0.809
AEN64633.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; CHASE4; KEGG: ent:Ent638_1913 periplasmic sensor diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
 
0.801
yhcK_2
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; KEGG: enc:ECL_00780 diguanylate cyclase; SMART: Diguanylate cyclase, predicted.
 
  
 0.795
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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