STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lsrKCarbohydrate kinase, FGGY; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. (531 aa)    
Predicted Functional Partners:
lsrR
PFAM: Putative sugar-binding region; KEGG: enc:ECL_04483 DeoR family transcriptional regulator.
 
  
 0.917
lsrB
KEGG: enc:ECL_04479 AI-2 transport system substrate-binding protein.
 
  
 0.907
lsrG
PFAM: Antibiotic biosynthesis monooxygenase; KEGG: enc:ECL_04477 autoinducer-2 (AI-2) modifying protein LsrG.
 
 
 0.905
lsrF_2
PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: enc:ECL_04478 aldolase.
 
  
 0.897
ptsH
KEGG: cro:ROD_23741 phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein; PFAM: Phosphotransferase system, phosphocarrier HPr protein.
    
   0.886
lsrD
ABC-type transporter, integral membrane subunit; PFAM: Bacterial inner-membrane translocator; KEGG: enc:ECL_04480 AI-2 transport system permease protein.
 
  
 0.838
AEN67069.1
TIGRFAM: Rhamnose isomerase; HAMAP: L-rhamnose isomerase; KEGG: ent:Ent638_4068 L-rhamnose isomerase; PFAM: Rhamnose isomerase.
 
 
 0.778
AEN67075.1
TIGRFAM: L-rhamnose 1-epimerase; HAMAP: L-rhamnose 1-epimerase; KEGG: ent:Ent638_4075 L-rhamnose 1-epimerase; PFAM: Rhamnose mutarotase.
  
  
 0.714
xylA_1
TIGRFAM: Xylose isomerase, bacterial type; HAMAP: Xylose isomerase; KEGG: enc:ECL_00201 xylose isomerase; PFAM: Xylose isomerase, TIM barrel domain.
 
 
 0.670
AEN67070.1
TIGRFAM: Rhamnose ABC transporter, rhamnose-binding; KEGG: ent:Ent638_4070 rhamnose ABC transporter, periplasmic rhamnose-binding protein.
 
  
 0.637
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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