STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa)    
Predicted Functional Partners:
ilvD_3
TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: enc:ECL_05011 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 0.993
metL_1
Aspartate kinase; KEGG: enc:ECL_05038 bifunctional aspartate kinase II/homoserine dehydrogenase II; TIGRFAM: Aspartate kinase region; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Aspartate/homoserine dehydrogenase, NAD-binding.
  
 
 0.951
leuA_2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.950
ilvM
KEGG: enc:ECL_05013 acetolactate synthase 2 regulatory subunit.
  
  
 0.940
leuA_1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.936
trpD_1
Anthranilate phosphoribosyltransferase; PFAM: Glycosyl transferase, family 3; Glutamine amidotransferase class-I, C-terminal; Glycosyl transferase, family 3, N-terminal; TIGRFAM: Anthranilate phosphoribosyl transferase; Glutamine amidotransferase of anthranilate synthase; HAMAP: Anthranilate phosphoribosyl transferase; KEGG: enc:ECL_01728 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase.
 
 
 0.925
pheA
Chorismate mutase; KEGG: enc:ECL_03929 bifunctional chorismate mutase/prephenate dehydratase; TIGRFAM: Chorismate mutase, gammaproteobacteria; PFAM: Prephenate dehydratase; Chorismate mutase, type II.
 
 
 0.925
putA_2
TIGRFAM: Delta-1-pyrroline-5-carboxylate dehydrogenase 3; KEGG: enc:ECL_02619 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase.
   
 0.914
ilvG
KEGG: enc:ECL_05014 acetolactate synthase 2 catalytic subunit; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
 
 
 0.906
avtA_3
PFAM: Aminotransferase, class I/II; KEGG: enc:ECL_00194 valine--pyruvate transaminase.
     
 0.882
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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