STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fieF_1Ferrous-iron efflux pump fieF; Cation-efflux transporter that may have a role in detoxification. (297 aa)    
Predicted Functional Partners:
cpxA_2
Integral membrane sensor signal transduction histidine kinase; KEGG: enc:ECL_05065 two-component system, OmpR family, sensor histidine kinase CpxA; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain.
 
   
 0.695
grxA
Glutaredoxin, GrxA family; KEGG: enc:ECL_02823 glutaredoxin 1; TIGRFAM: Glutaredoxin, GrxA; PFAM: Glutaredoxin.
  
  
 0.678
wzb
KEGG: enc:ECL_03384 tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight.
 
   
 0.674
otsA
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
  
   
 0.665
copA_3
Copper-translocating P-type ATPase; KEGG: enc:ECL_01253 copper exporting ATPase; TIGRFAM: ATPase, P type, cation/copper-transporter; ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase.
 
 
 0.655
amtB
KEGG: enc:ECL_01212 ammonium transporter; TIGRFAM: Ammonium transporter; PFAM: Ammonium transporter.
   
  
 0.633
gor
KEGG: enc:ECL_04917 glutathione reductase; TIGRFAM: Glutathione reductase, animal/bacterial; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
  
  
 0.628
otsB
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
     
 0.623
wzc
Capsular exopolysaccharide family; KEGG: ent:Ent638_2674 tyrosine kinase; TIGRFAM: Exopolysaccharide synthesis protein; PFAM: Lipopolysaccharide biosynthesis.
     
 0.623
bcp
PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: cro:ROD_24291 putative peroxiredoxin (bacterioferritin comigratory protein).
     
 0.623
Your Current Organism:
Enterobacter asburiae
NCBI taxonomy Id: 640513
Other names: E. asburiae LF7a, Enterobacter asburiae LF7a, Enterobacter asburiae str. LF7a, Enterobacter asburiae strain LF7a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.