STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcdGlucose dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway; Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily. (356 aa)    
Predicted Functional Partners:
gapB
Glyceraldehyde 3-phosphate dehydrogenase; GapB.
  
 
 0.879
pgi
Peroxidase / catalase; Pgi.
  
 0.873
gap
Glyceraldehyde-3-phosphate dehydrogenase; Gap; Belongs to the aldehyde dehydrogenase family.
  
 0.860
purB
Adenylosuccinate lyase; PurB.
  
  
 0.859
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.852
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.850
glcK
Glucose kinase; GlcK.
  
 
 0.843
pdhA1
Pyruvate dehydrogenase alpha subunit; PdhA1.
  
 
 0.837
VNG_0683C
Conserved hypothetical protein; Has aldolase activity with fructose 1,6-bisphosphate. May play a role in the biosynthesis of aromatic amino acids (AroAA).
 
 
  0.836
pdhA2
Pyruvate dehydrogenase alpha subunit; PdhA2.
  
 
 0.835
Your Current Organism:
Halobacterium salinarum
NCBI taxonomy Id: 64091
Other names: H. salinarum NRC-1, Halobacterium halobium NRC-1, Halobacterium salinarum NRC-1, Halobacterium salinarum str. NRC-1, Halobacterium salinarum strain NRC-1, Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081), Halobacterium sp. (strain NRC-1), Halobacterium sp. ATCC 700922, Halobacterium sp. JCM 11081, Halobacterium sp. NRC-1
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