Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pyrHConserved hypothetical protein; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa)    
Predicted Functional Partners:
lysS
lysyl-tRNA synthetase; LysS; Belongs to the class-I aminoacyl-tRNA synthetase family.
      0.994
VNG_2019C
Conserved hypothetical protein; Vng2019c.
  
  
 0.980
upp
Conserved hypothetical protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
 
 0.972
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 
 0.954
urk
Uridine kinase; Urk.
  
 
 0.952
pyrF
Orotidine-5'-monophosphate (Ura3); PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.951
surE
Stationary phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.946
rps2p
30S ribosomal protein S2P; Rps2p; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.945
moaE
Molybdenum cofactor biosynthesis protein; MoaE.
  
    0.908
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.803
Your Current Organism:
Halobacterium salinarum
NCBI taxonomy Id: 64091
Other names: H. salinarum NRC-1, Halobacterium halobium NRC-1, Halobacterium salinarum NRC-1, Halobacterium salinarum str. NRC-1, Halobacterium salinarum strain NRC-1, Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081), Halobacterium sp. (strain NRC-1), Halobacterium sp. ATCC 700922, Halobacterium sp. JCM 11081, Halobacterium sp. NRC-1
Server load: low (16%) [HD]