Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VNG_2019CConserved hypothetical protein; Vng2019c. (600 aa)    
Predicted Functional Partners:
pyrH
Conserved hypothetical protein; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.980
lysS
lysyl-tRNA synthetase; LysS; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.970
VNG_2021C
Conserved hypothetical protein; Vng2021c; In the N-terminal section; belongs to the UPF0447 family.
       0.931
VNG_2155C
Conserved hypothetical protein; Vng2155c.
 
     0.812
ncsA
Conserved hypothetical protein; Vng0190c.
  
    0.720
VNG_1781C
Conserved hypothetical protein; Vng1781c.
 
  
 0.694
moaE
Molybdenum cofactor biosynthesis protein; MoaE.
       0.677
uppS
Conserved hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
  
 0.654
celM
Endoglucanase; CelM.
      
 0.635
VNG_0361C
Conserved hypothetical protein; Vng0361c.
 
  
 0.629
Your Current Organism:
Halobacterium salinarum
NCBI taxonomy Id: 64091
Other names: H. salinarum NRC-1, Halobacterium halobium NRC-1, Halobacterium salinarum NRC-1, Halobacterium salinarum str. NRC-1, Halobacterium salinarum strain NRC-1, Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081), Halobacterium sp. (strain NRC-1), Halobacterium sp. ATCC 700922, Halobacterium sp. JCM 11081, Halobacterium sp. NRC-1
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