Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VNG_2020CConserved hypothetical protein; Vng2020c. (176 aa)    
Predicted Functional Partners:
VNG_2021C
Conserved hypothetical protein; Vng2021c; In the N-terminal section; belongs to the UPF0447 family.
       0.670
nthA2
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.615
VNG_0669H
Hypothetical protein; Vng0669h.
 
     0.548
VNG_0727C
Conserved hypothetical protein; Vng0727c.
 
    0.424
nosF2
Copper transport ATP-binding protein; NosF2.
  
    0.421
trp3
Daunorubicin resistance ABC transporter ATP-binding protein; Trp3.
  
    0.421
VNG_0668C
Conserved hypothetical protein; Vng0668c.
  
    0.421
trp5
ABC transporter, ATP-binding protein; Trp5.
  
    0.421
trp2
ABC transport protein; Trp2.
  
    0.421
nosF1
Copper transport ATP-binding protein; NosF1.
  
    0.421
Your Current Organism:
Halobacterium salinarum
NCBI taxonomy Id: 64091
Other names: H. salinarum NRC-1, Halobacterium halobium NRC-1, Halobacterium salinarum NRC-1, Halobacterium salinarum str. NRC-1, Halobacterium salinarum strain NRC-1, Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081), Halobacterium sp. (strain NRC-1), Halobacterium sp. ATCC 700922, Halobacterium sp. JCM 11081, Halobacterium sp. NRC-1
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