STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutS3Mismatch repair protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (669 aa)    
Predicted Functional Partners:
mutS1
Mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity).
 
 
 0.976
mutS2
Mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity).
 
 
0.928
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.829
orc6
Orc / cell division control protein 6; Involved in regulation of DNA replication. Belongs to the CDC6/cdc18 family.
 
    0.796
uvrD
Repair helicase; UvrD.
 
  
 0.779
rps4p
30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
   0.771
tatC1
Protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
 
    0.716
lta
L-allo-threonine aldolase; Lta.
   
    0.698
uvrC
Excision nuclease chain C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
  
 0.693
uvrA
Excision nuclease chain A; UvrA.
 
   
 0.692
Your Current Organism:
Halobacterium salinarum
NCBI taxonomy Id: 64091
Other names: H. salinarum NRC-1, Halobacterium halobium NRC-1, Halobacterium salinarum NRC-1, Halobacterium salinarum str. NRC-1, Halobacterium salinarum strain NRC-1, Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081), Halobacterium sp. (strain NRC-1), Halobacterium sp. ATCC 700922, Halobacterium sp. JCM 11081, Halobacterium sp. NRC-1
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