node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroA | tnaA | VNG_0309C | VNG_2373G | Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | Tryptophanase; TnaA. | 0.649 |
aroA | trpA | VNG_0309C | VNG_0308G | Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.963 |
aroA | trpB | VNG_0309C | VNG_0307G | Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.836 |
ftsZ1 | pyrE2 | VNG_0376G | VNG_2118G | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Orotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.449 |
ftsZ1 | tnaA | VNG_0376G | VNG_2373G | Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Tryptophanase; TnaA. | 0.582 |
iluA | lysC | VNG_2100G | VNG_2374G | Threonine dehydratase; IluA. | Aspartokinase II alpha subunit; LysC; Belongs to the aspartokinase family. | 0.711 |
iluA | tnaA | VNG_2100G | VNG_2373G | Threonine dehydratase; IluA. | Tryptophanase; TnaA. | 0.632 |
iluA | trpA | VNG_2100G | VNG_0308G | Threonine dehydratase; IluA. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.945 |
iluA | trpB | VNG_2100G | VNG_0307G | Threonine dehydratase; IluA. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.971 |
lpb | mvaA | VNG_0062G | VNG_1875G | LPS biosynthesis protein; Lpb. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; MvaA; Belongs to the HMG-CoA reductase family. | 0.516 |
lpb | tnaA | VNG_0062G | VNG_2373G | LPS biosynthesis protein; Lpb. | Tryptophanase; TnaA. | 0.501 |
lysC | iluA | VNG_2374G | VNG_2100G | Aspartokinase II alpha subunit; LysC; Belongs to the aspartokinase family. | Threonine dehydratase; IluA. | 0.711 |
lysC | tnaA | VNG_2374G | VNG_2373G | Aspartokinase II alpha subunit; LysC; Belongs to the aspartokinase family. | Tryptophanase; TnaA. | 0.790 |
lysC | trpA | VNG_2374G | VNG_0308G | Aspartokinase II alpha subunit; LysC; Belongs to the aspartokinase family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.512 |
lysC | trpB | VNG_2374G | VNG_0307G | Aspartokinase II alpha subunit; LysC; Belongs to the aspartokinase family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.475 |
mvaA | lpb | VNG_1875G | VNG_0062G | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; MvaA; Belongs to the HMG-CoA reductase family. | LPS biosynthesis protein; Lpb. | 0.516 |
mvaA | pyrE2 | VNG_1875G | VNG_2118G | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; MvaA; Belongs to the HMG-CoA reductase family. | Orotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.748 |
mvaA | tnaA | VNG_1875G | VNG_2373G | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; MvaA; Belongs to the HMG-CoA reductase family. | Tryptophanase; TnaA. | 0.562 |
mvaA | trpA | VNG_1875G | VNG_0308G | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; MvaA; Belongs to the HMG-CoA reductase family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.523 |
pyrE1 | pyrE2 | VNG_0448G | VNG_2118G | Aspartate carbamoyltransferase catalytic subunit; PyrE1; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.964 |