Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
VNG_2452CConserved hypothetical protein; Vng2452c; Belongs to the UPF0200 family. (190 aa)    
Predicted Functional Partners:
VNG_2454C
Conserved hypothetical protein; Vng2454c; Belongs to the UPF0201 family.
 
    0.994
VNG_0250C
Conserved hypothetical protein; Vng0250c.
 
     0.782
uvrA
Excision nuclease chain A; UvrA.
 
  
 0.692
rnh
RNAase H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.658
vacB
Ribonuclease II family protein; VacB.
  
  
 0.658
cca
tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
 
     0.634
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.620
dfp
Pantothenate metabolism flavoprotein; Dfp.
  
 
 0.616
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
     
 0.605
gapB
Glyceraldehyde 3-phosphate dehydrogenase; GapB.
 
   
 0.587
Your Current Organism:
Halobacterium salinarum
NCBI taxonomy Id: 64091
Other names: H. salinarum NRC-1, Halobacterium halobium NRC-1, Halobacterium salinarum NRC-1, Halobacterium salinarum str. NRC-1, Halobacterium salinarum strain NRC-1, Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081), Halobacterium sp. (strain NRC-1), Halobacterium sp. ATCC 700922, Halobacterium sp. JCM 11081, Halobacterium sp. NRC-1
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