node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFD58453.1 | SFD58476.1 | SAMN05216238_102295 | SAMN05216238_102296 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.993 |
SFD58453.1 | SFD58534.1 | SAMN05216238_102295 | SAMN05216238_102298 | Porphobilinogen synthase; Belongs to the ALAD family. | HemX family protein. | 0.844 |
SFD58453.1 | SFD89872.1 | SAMN05216238_102295 | SAMN05216238_105197 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.956 |
SFD58453.1 | SFD89913.1 | SAMN05216238_102295 | SAMN05216238_105199 | Porphobilinogen synthase; Belongs to the ALAD family. | Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. | 0.857 |
SFD58453.1 | SFD89930.1 | SAMN05216238_102295 | SAMN05216238_105200 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III synthase. | 0.883 |
SFD58453.1 | hemA | SAMN05216238_102295 | SAMN05216238_102299 | Porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.952 |
SFD58453.1 | hemC | SAMN05216238_102295 | SAMN05216238_102297 | Porphobilinogen synthase; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
SFD58453.1 | hemE | SAMN05216238_102295 | SAMN05216238_10133 | Porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.704 |
SFD58453.1 | hemL | SAMN05216238_102295 | SAMN05216238_102294 | Porphobilinogen synthase; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.997 |
SFD58453.1 | hemL-2 | SAMN05216238_102295 | SAMN05216238_112104 | Porphobilinogen synthase; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.992 |
SFD58476.1 | SFD58453.1 | SAMN05216238_102296 | SAMN05216238_102295 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.993 |
SFD58476.1 | SFD58534.1 | SAMN05216238_102296 | SAMN05216238_102298 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | HemX family protein. | 0.935 |
SFD58476.1 | SFD89872.1 | SAMN05216238_102296 | SAMN05216238_105197 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.996 |
SFD58476.1 | SFD89913.1 | SAMN05216238_102296 | SAMN05216238_105199 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. | 0.780 |
SFD58476.1 | SFD89930.1 | SAMN05216238_102296 | SAMN05216238_105200 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrinogen-III synthase. | 0.920 |
SFD58476.1 | hemA | SAMN05216238_102296 | SAMN05216238_102299 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.948 |
SFD58476.1 | hemC | SAMN05216238_102296 | SAMN05216238_102297 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
SFD58476.1 | hemE | SAMN05216238_102296 | SAMN05216238_10133 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.938 |
SFD58476.1 | hemL | SAMN05216238_102296 | SAMN05216238_102294 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.945 |
SFD58476.1 | hemL-2 | SAMN05216238_102296 | SAMN05216238_112104 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.808 |