node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFD81531.1 | SFD81552.1 | SAMN05216238_104203 | SAMN05216238_104204 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.999 |
SFD81531.1 | SFD88287.1 | SAMN05216238_104203 | SAMN05216238_105118 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | L-threonine ammonia-lyase. | 0.894 |
SFD81531.1 | SFE17575.1 | SAMN05216238_104203 | SAMN05216238_109119 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Homoserine dehydrogenase. | 0.776 |
SFD81531.1 | SFE20944.1 | SAMN05216238_104203 | SAMN05216238_11021 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase. | 0.918 |
SFD81531.1 | SFE21954.1 | SAMN05216238_104203 | SAMN05216238_11063 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase. | 0.918 |
SFD81531.1 | SFE42121.1 | SAMN05216238_104203 | SAMN05216238_11574 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine O-acetyltransferase. | 0.911 |
SFD81531.1 | dsdA | SAMN05216238_104203 | SAMN05216238_10441 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | D-serine ammonia-lyase; Belongs to the serine/threonine dehydratase family. DsdA subfamily. | 0.917 |
SFD81531.1 | glyA | SAMN05216238_104203 | SAMN05216238_10876 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.953 |
SFD81531.1 | thrB | SAMN05216238_104203 | SAMN05216238_109117 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.798 |
SFD81531.1 | trpA | SAMN05216238_104203 | SAMN05216238_10953 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.908 |
SFD81552.1 | SFD81531.1 | SAMN05216238_104204 | SAMN05216238_104203 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.999 |
SFD81552.1 | SFD88287.1 | SAMN05216238_104204 | SAMN05216238_105118 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | L-threonine ammonia-lyase. | 0.897 |
SFD81552.1 | SFE17575.1 | SAMN05216238_104204 | SAMN05216238_109119 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Homoserine dehydrogenase. | 0.776 |
SFD81552.1 | SFE20944.1 | SAMN05216238_104204 | SAMN05216238_11021 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase. | 0.920 |
SFD81552.1 | SFE21954.1 | SAMN05216238_104204 | SAMN05216238_11063 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase. | 0.920 |
SFD81552.1 | SFE42121.1 | SAMN05216238_104204 | SAMN05216238_11574 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine O-acetyltransferase. | 0.911 |
SFD81552.1 | dsdA | SAMN05216238_104204 | SAMN05216238_10441 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | D-serine ammonia-lyase; Belongs to the serine/threonine dehydratase family. DsdA subfamily. | 0.917 |
SFD81552.1 | glyA | SAMN05216238_104204 | SAMN05216238_10876 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.954 |
SFD81552.1 | thrB | SAMN05216238_104204 | SAMN05216238_109117 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.798 |
SFD81552.1 | trpA | SAMN05216238_104204 | SAMN05216238_10953 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.908 |