STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFE18616.13-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (429 aa)    
Predicted Functional Partners:
SFD39621.1
hydroxymethylglutaryl-CoA synthase.
 
 0.999
SFE18568.1
Diphosphomevalonate decarboxylase.
 
 
 0.998
SFE18592.1
Mevalonate kinase.
 0.988
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 0.908
SFE37343.1
2-polyprenyl-6-methoxyphenol hydroxylase.
   
  
 0.863
SFE18539.1
Phosphomevalonate kinase.
 
 0.848
SFD95183.1
3-hydroxyacyl-CoA dehydrogenase.
    
 0.822
SFD95934.1
1,4-dihydroxy-2-naphthoate prenyltransferase.
    
 
 0.820
menA
1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 
 0.820
SFE17382.1
Farnesyl-diphosphate farnesyltransferase.
  
 
 0.673
Your Current Organism:
Lentibacillus persicus
NCBI taxonomy Id: 640948
Other names: CCM 7683, CECT 7524, DSM 22530, L. persicus, LMG 25304, LMG:25304, Lentibacillus persicus Sanchez-Porro et al. 2010, Lentibacillus sp. Amb31, strain Amb31
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