node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFD61620.1 | SFE15899.1 | SAMN05216238_102432 | SAMN05216238_10948 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | 0.969 |
SFD61620.1 | aroE | SAMN05216238_102432 | SAMN05216238_102211 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.964 |
SFD61620.1 | guaB | SAMN05216238_102432 | SAMN05216238_103270 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.410 |
SFD61620.1 | menF | SAMN05216238_102432 | SAMN05216238_10624 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.968 |
SFD61620.1 | trpA | SAMN05216238_102432 | SAMN05216238_10953 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.613 |
SFD61620.1 | trpB | SAMN05216238_102432 | SAMN05216238_10952 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.466 |
SFD61620.1 | trpC | SAMN05216238_102432 | SAMN05216238_10950 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.802 |
SFD61620.1 | trpD | SAMN05216238_102432 | SAMN05216238_10949 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Anthranilate phosphoribosyltransferase/anthranilate synthase/phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.962 |
SFD61620.1 | trpE | SAMN05216238_102432 | SAMN05216238_10947 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.966 |
SFD61620.1 | trpF | SAMN05216238_102432 | SAMN05216238_10951 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.764 |
SFE15899.1 | SFD61620.1 | SAMN05216238_10948 | SAMN05216238_102432 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | 0.969 |
SFE15899.1 | aroE | SAMN05216238_10948 | SAMN05216238_102211 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.866 |
SFE15899.1 | guaB | SAMN05216238_10948 | SAMN05216238_103270 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.935 |
SFE15899.1 | menF | SAMN05216238_10948 | SAMN05216238_10624 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.853 |
SFE15899.1 | trpA | SAMN05216238_10948 | SAMN05216238_10953 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.996 |
SFE15899.1 | trpB | SAMN05216238_10948 | SAMN05216238_10952 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
SFE15899.1 | trpC | SAMN05216238_10948 | SAMN05216238_10950 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
SFE15899.1 | trpD | SAMN05216238_10948 | SAMN05216238_10949 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | Anthranilate phosphoribosyltransferase/anthranilate synthase/phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
SFE15899.1 | trpE | SAMN05216238_10948 | SAMN05216238_10947 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.999 |
SFE15899.1 | trpF | SAMN05216238_10948 | SAMN05216238_10951 | Anthranilate synthase component 2/anthranilate synthase/phosphoribosyltransferase. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.999 |