node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFD61620.1 | SFE45849.1 | SAMN05216238_102432 | SAMN05216238_11716 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Prephenate dehydrogenase. | 0.993 |
SFD61620.1 | aroA | SAMN05216238_102432 | SAMN05216238_11717 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.999 |
SFD61620.1 | aroB | SAMN05216238_102432 | SAMN05216238_11714 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.997 |
SFD61620.1 | aroC | SAMN05216238_102432 | SAMN05216238_11713 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.999 |
SFD61620.1 | aroE | SAMN05216238_102432 | SAMN05216238_102211 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.964 |
SFD61620.1 | aroK | SAMN05216238_102432 | SAMN05216238_102118 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.995 |
SFD61620.1 | hisC-2 | SAMN05216238_102432 | SAMN05216238_11715 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.950 |
SFD61620.1 | menF | SAMN05216238_102432 | SAMN05216238_10624 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.968 |
SFD61620.1 | trpA | SAMN05216238_102432 | SAMN05216238_10953 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.613 |
SFD61620.1 | trpE | SAMN05216238_102432 | SAMN05216238_10947 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.966 |
SFE45849.1 | SFD61620.1 | SAMN05216238_11716 | SAMN05216238_102432 | Prephenate dehydrogenase. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase. | 0.993 |
SFE45849.1 | aroA | SAMN05216238_11716 | SAMN05216238_11717 | Prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.998 |
SFE45849.1 | aroB | SAMN05216238_11716 | SAMN05216238_11714 | Prephenate dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.962 |
SFE45849.1 | aroC | SAMN05216238_11716 | SAMN05216238_11713 | Prephenate dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.990 |
SFE45849.1 | aroE | SAMN05216238_11716 | SAMN05216238_102211 | Prephenate dehydrogenase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.485 |
SFE45849.1 | aroK | SAMN05216238_11716 | SAMN05216238_102118 | Prephenate dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.795 |
SFE45849.1 | hisC-2 | SAMN05216238_11716 | SAMN05216238_11715 | Prephenate dehydrogenase. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.995 |
SFE45849.1 | menF | SAMN05216238_11716 | SAMN05216238_10624 | Prephenate dehydrogenase. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.576 |
SFE45849.1 | trpA | SAMN05216238_11716 | SAMN05216238_10953 | Prephenate dehydrogenase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.687 |
SFE45849.1 | trpE | SAMN05216238_11716 | SAMN05216238_10947 | Prephenate dehydrogenase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.673 |