node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFD88190.1 | SFE48689.1 | SAMN05216238_105114 | SAMN05216238_1198 | GAF domain-containing protein. | Hypothetical protein. | 0.690 |
SFE48661.1 | SFE48689.1 | SAMN05216238_1197 | SAMN05216238_1198 | Enoyl-[acyl-carrier-protein] reductase [NADH]. | Hypothetical protein. | 0.513 |
SFE48689.1 | SFD88190.1 | SAMN05216238_1198 | SAMN05216238_105114 | Hypothetical protein. | GAF domain-containing protein. | 0.690 |
SFE48689.1 | SFE48661.1 | SAMN05216238_1198 | SAMN05216238_1197 | Hypothetical protein. | Enoyl-[acyl-carrier-protein] reductase [NADH]. | 0.513 |
SFE48689.1 | SFE48722.1 | SAMN05216238_1198 | SAMN05216238_1199 | Hypothetical protein. | Protein of unknown function. | 0.530 |
SFE48689.1 | cinA | SAMN05216238_1198 | SAMN05216238_10495 | Hypothetical protein. | Competence/damage-inducible protein cinA; Belongs to the CinA family. | 0.850 |
SFE48689.1 | guaB | SAMN05216238_1198 | SAMN05216238_103270 | Hypothetical protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.802 |
SFE48689.1 | gyrB | SAMN05216238_1198 | SAMN05216238_103266 | Hypothetical protein. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.444 |
SFE48689.1 | parE | SAMN05216238_1198 | SAMN05216238_10454 | Hypothetical protein. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. | 0.444 |
SFE48689.1 | scpA | SAMN05216238_1198 | SAMN05216238_10231 | Hypothetical protein. | Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.823 |
SFE48722.1 | SFE48689.1 | SAMN05216238_1199 | SAMN05216238_1198 | Protein of unknown function. | Hypothetical protein. | 0.530 |
cinA | SFE48689.1 | SAMN05216238_10495 | SAMN05216238_1198 | Competence/damage-inducible protein cinA; Belongs to the CinA family. | Hypothetical protein. | 0.850 |
guaB | SFE48689.1 | SAMN05216238_103270 | SAMN05216238_1198 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Hypothetical protein. | 0.802 |
guaB | gyrB | SAMN05216238_103270 | SAMN05216238_103266 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.529 |
guaB | parE | SAMN05216238_103270 | SAMN05216238_10454 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. | 0.529 |
gyrB | SFE48689.1 | SAMN05216238_103266 | SAMN05216238_1198 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein. | 0.444 |
gyrB | guaB | SAMN05216238_103266 | SAMN05216238_103270 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.529 |
parE | SFE48689.1 | SAMN05216238_10454 | SAMN05216238_1198 | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. | Hypothetical protein. | 0.444 |
parE | guaB | SAMN05216238_10454 | SAMN05216238_103270 | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.529 |
scpA | SFE48689.1 | SAMN05216238_10231 | SAMN05216238_1198 | Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Hypothetical protein. | 0.823 |