STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDP48013.1Serine protease, S1-C subfamily, contains C-terminal PDZ domain. (506 aa)    
Predicted Functional Partners:
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
 0.948
tatB
Sec-independent protein translocase protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
  
    0.784
secF
SecD/SecF fusion protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
 
 0.761
SDN90868.1
Putative serine protease PepD.
  
  
 
0.754
SDP48036.1
Hypothetical protein.
 
     0.743
SDP22705.1
Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN metalloenzyme (JAMM) motif.
   
  0.691
rplK
Large subunit ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
   0.656
SDO65478.1
PAS domain S-box-containing protein.
  
  
 0.637
rpsF
Small subunit ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.632
SDP48052.1
RNA polymerase sigma-70 factor, ECF subfamily.
  
    0.621
Your Current Organism:
Lentzea jiangxiensis
NCBI taxonomy Id: 641025
Other names: CGMCC 4.6609, L. jiangxiensis, Lentzea jiangxiensis Li et al. 2012, Lentzea sp. FXJ1.034, NBRC 106680, strain FXJ1.034
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.