STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ku-2DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (275 aa)    
Predicted Functional Partners:
SDP65950.1
Bifunctional non-homologous end joining protein LigD.
 
  
 0.971
SDP65932.1
Bifunctional non-homologous end joining protein LigD.
 
  
 0.958
SDP95275.1
ATP-dependent DNA ligase.
 
  
 0.870
SDP04524.1
ATP-dependent DNA ligase.
 
  
 0.868
SDP03993.1
DNA ligase D.
 
  
 0.850
SDP95236.1
DNA ligase D.
 
  
 0.850
SDP03962.1
DNA ligase D, polymerase domain-containing protein.
 
  
 0.840
SDO47838.1
Bifunctional non-homologous end joining protein LigD.
 
  
 0.825
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
  
  
 
0.748
SDP06334.1
DNA end-binding protein Ku.
  
  
 
0.738
Your Current Organism:
Lentzea jiangxiensis
NCBI taxonomy Id: 641025
Other names: CGMCC 4.6609, L. jiangxiensis, Lentzea jiangxiensis Li et al. 2012, Lentzea sp. FXJ1.034, NBRC 106680, strain FXJ1.034
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.