STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDP85218.1SPFH domain / Band 7 family protein. (213 aa)    
Predicted Functional Partners:
ftsH
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.952
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.645
SDP78242.1
Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.
   
    0.633
SDP53323.1
Hypothetical protein.
  
  
 0.584
SDO05619.1
Predicted Zn-dependent peptidase; Belongs to the peptidase M16 family.
  
 0.565
SDP96741.1
Predicted Zn-dependent peptidase.
  
 0.565
SDP96746.1
Predicted Zn-dependent peptidase.
  
 0.565
SDO02909.1
Hypothetical protein.
   
    0.560
SDP22605.1
Membrane associated serine protease, rhomboid family.
   
 0.555
SDP77662.1
Membrane associated serine protease, rhomboid family.
   
 0.555
Your Current Organism:
Lentzea jiangxiensis
NCBI taxonomy Id: 641025
Other names: CGMCC 4.6609, L. jiangxiensis, Lentzea jiangxiensis Li et al. 2012, Lentzea sp. FXJ1.034, NBRC 106680, strain FXJ1.034
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.