node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDO58332.1 | egtB | SAMN05421507_10334 | SAMN05421507_13341 | Hypothetical protein. | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.781 |
SDO85032.1 | egtB | SAMN05421507_104163 | SAMN05421507_13341 | Glutamate-cysteine ligase family 2(GCS2). | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.758 |
SDP02806.1 | egtA | SAMN05421507_1055 | SAMN05421507_13342 | Glutamine amidotransferase. | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.665 |
SDP02806.1 | egtB | SAMN05421507_1055 | SAMN05421507_13341 | Glutamine amidotransferase. | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.962 |
SDP02806.1 | egtD | SAMN05421507_1055 | SAMN05421507_13339 | Glutamine amidotransferase. | L-histidine Nalpha-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.839 |
SDP08112.1 | egtB | SAMN05421507_105185 | SAMN05421507_13341 | Hypothetical protein. | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.758 |
SDP88353.1 | egtB | SAMN05421507_118100 | SAMN05421507_13341 | Hypothetical protein. | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.781 |
SDP91136.1 | egtB | SAMN05421507_12025 | SAMN05421507_13341 | Deoxyribonuclease-4. | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.696 |
SDP91136.1 | pyrF | SAMN05421507_12025 | SAMN05421507_105251 | Deoxyribonuclease-4. | Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.703 |
egtA | SDP02806.1 | SAMN05421507_13342 | SAMN05421507_1055 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Glutamine amidotransferase. | 0.665 |
egtA | egtB | SAMN05421507_13342 | SAMN05421507_13341 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.998 |
egtA | egtC | SAMN05421507_13342 | SAMN05421507_13340 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.966 |
egtA | egtD | SAMN05421507_13342 | SAMN05421507_13339 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | L-histidine Nalpha-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.982 |
egtB | SDO58332.1 | SAMN05421507_13341 | SAMN05421507_10334 | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Hypothetical protein. | 0.781 |
egtB | SDO85032.1 | SAMN05421507_13341 | SAMN05421507_104163 | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamate-cysteine ligase family 2(GCS2). | 0.758 |
egtB | SDP02806.1 | SAMN05421507_13341 | SAMN05421507_1055 | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamine amidotransferase. | 0.962 |
egtB | SDP08112.1 | SAMN05421507_13341 | SAMN05421507_105185 | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Hypothetical protein. | 0.758 |
egtB | SDP88353.1 | SAMN05421507_13341 | SAMN05421507_118100 | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Hypothetical protein. | 0.781 |
egtB | SDP91136.1 | SAMN05421507_13341 | SAMN05421507_12025 | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Deoxyribonuclease-4. | 0.696 |
egtB | egtA | SAMN05421507_13341 | SAMN05421507_13342 | iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.998 |