node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHI97044.1 | EHI97172.1 | CDLVIII_0307 | CDLVIII_0435 | TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; KEGG: cbe:Cbei_0068 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.579 |
EHI97044.1 | EHI97218.1 | CDLVIII_0307 | CDLVIII_0483 | TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; KEGG: cbe:Cbei_0068 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.412 |
EHI97044.1 | queE | CDLVIII_0307 | CDLVIII_3473 | TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; KEGG: cbe:Cbei_0068 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.807 |
EHI97172.1 | EHI97044.1 | CDLVIII_0435 | CDLVIII_0307 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; KEGG: cbe:Cbei_0068 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone. | 0.579 |
EHI97172.1 | EHI97218.1 | CDLVIII_0435 | CDLVIII_0483 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.860 |
EHI97172.1 | EHJ00670.1 | CDLVIII_0435 | CDLVIII_4139 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | KEGG: cbe:Cbei_2522 ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; TIGRFAM: Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent. | 0.536 |
EHI97172.1 | folE | CDLVIII_0435 | CDLVIII_3472 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; TIGRFAM: GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; KEGG: cbe:Cbei_2540 GTP cyclohydrolase I. | 0.835 |
EHI97172.1 | queE | CDLVIII_0435 | CDLVIII_3473 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.924 |
EHI97218.1 | EHI97044.1 | CDLVIII_0483 | CDLVIII_0307 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; KEGG: cbe:Cbei_0068 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone. | 0.412 |
EHI97218.1 | EHI97172.1 | CDLVIII_0483 | CDLVIII_0435 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.860 |
EHI97218.1 | EHJ00035.1 | CDLVIII_0483 | CDLVIII_3474 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | PFAM: 6-pyruvoyl tetrahydropterin synthase-related; KEGG: cbe:Cbei_2538 6-pyruvoyl tetrahydrobiopterin synthase, putative. | 0.882 |
EHI97218.1 | EHJ00670.1 | CDLVIII_0483 | CDLVIII_4139 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: cbe:Cbei_2522 ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; TIGRFAM: Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent. | 0.412 |
EHI97218.1 | folE | CDLVIII_0483 | CDLVIII_3472 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; TIGRFAM: GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; KEGG: cbe:Cbei_2540 GTP cyclohydrolase I. | 0.999 |
EHI97218.1 | purF | CDLVIII_0483 | CDLVIII_1603 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.489 |
EHI97218.1 | queE | CDLVIII_0483 | CDLVIII_3473 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.856 |
EHJ00035.1 | EHI97218.1 | CDLVIII_3474 | CDLVIII_0483 | PFAM: 6-pyruvoyl tetrahydropterin synthase-related; KEGG: cbe:Cbei_2538 6-pyruvoyl tetrahydrobiopterin synthase, putative. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.882 |
EHJ00035.1 | folE | CDLVIII_3474 | CDLVIII_3472 | PFAM: 6-pyruvoyl tetrahydropterin synthase-related; KEGG: cbe:Cbei_2538 6-pyruvoyl tetrahydrobiopterin synthase, putative. | PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; TIGRFAM: GTP cyclohydrolase I; HAMAP: GTP cyclohydrolase I; KEGG: cbe:Cbei_2540 GTP cyclohydrolase I. | 0.995 |
EHJ00035.1 | queC | CDLVIII_3474 | CDLVIII_3471 | PFAM: 6-pyruvoyl tetrahydropterin synthase-related; KEGG: cbe:Cbei_2538 6-pyruvoyl tetrahydrobiopterin synthase, putative. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.983 |
EHJ00035.1 | queE | CDLVIII_3474 | CDLVIII_3473 | PFAM: 6-pyruvoyl tetrahydropterin synthase-related; KEGG: cbe:Cbei_2538 6-pyruvoyl tetrahydrobiopterin synthase, putative. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
EHJ00035.1 | queF | CDLVIII_3474 | CDLVIII_3470 | PFAM: 6-pyruvoyl tetrahydropterin synthase-related; KEGG: cbe:Cbei_2538 6-pyruvoyl tetrahydrobiopterin synthase, putative. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.959 |