node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFG30352.1 | EFG30743.1 | HMPREF9021_01849 | HMPREF9021_01349 | 2Fe-2S ferredoxin. | Iron-binding protein iscA; Belongs to the HesB/IscA family. | 0.870 |
EFG30352.1 | EFG30744.1 | HMPREF9021_01849 | HMPREF9021_01350 | 2Fe-2S ferredoxin. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.946 |
EFG30352.1 | EFG31534.1 | HMPREF9021_01849 | HMPREF9021_00804 | 2Fe-2S ferredoxin. | FeS assembly protein IscX. | 0.959 |
EFG30352.1 | cyaY | HMPREF9021_01849 | HMPREF9021_01003 | 2Fe-2S ferredoxin. | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.874 |
EFG30352.1 | hscA | HMPREF9021_01849 | HMPREF9021_02206 | 2Fe-2S ferredoxin. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.850 |
EFG30352.1 | hscB | HMPREF9021_01849 | HMPREF9021_00004 | 2Fe-2S ferredoxin. | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.960 |
EFG30352.1 | iscS | HMPREF9021_01849 | HMPREF9021_01355 | 2Fe-2S ferredoxin. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.888 |
EFG30743.1 | EFG30352.1 | HMPREF9021_01349 | HMPREF9021_01849 | Iron-binding protein iscA; Belongs to the HesB/IscA family. | 2Fe-2S ferredoxin. | 0.870 |
EFG30743.1 | EFG30744.1 | HMPREF9021_01349 | HMPREF9021_01350 | Iron-binding protein iscA; Belongs to the HesB/IscA family. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.946 |
EFG30743.1 | EFG31534.1 | HMPREF9021_01349 | HMPREF9021_00804 | Iron-binding protein iscA; Belongs to the HesB/IscA family. | FeS assembly protein IscX. | 0.618 |
EFG30743.1 | hscA | HMPREF9021_01349 | HMPREF9021_02206 | Iron-binding protein iscA; Belongs to the HesB/IscA family. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.643 |
EFG30743.1 | hscB | HMPREF9021_01349 | HMPREF9021_00004 | Iron-binding protein iscA; Belongs to the HesB/IscA family. | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.908 |
EFG30743.1 | iscS | HMPREF9021_01349 | HMPREF9021_01355 | Iron-binding protein iscA; Belongs to the HesB/IscA family. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.867 |
EFG30744.1 | EFG30352.1 | HMPREF9021_01350 | HMPREF9021_01849 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 2Fe-2S ferredoxin. | 0.946 |
EFG30744.1 | EFG30743.1 | HMPREF9021_01350 | HMPREF9021_01349 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Iron-binding protein iscA; Belongs to the HesB/IscA family. | 0.946 |
EFG30744.1 | EFG31534.1 | HMPREF9021_01350 | HMPREF9021_00804 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | FeS assembly protein IscX. | 0.722 |
EFG30744.1 | cyaY | HMPREF9021_01350 | HMPREF9021_01003 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.996 |
EFG30744.1 | hscA | HMPREF9021_01350 | HMPREF9021_02206 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.754 |
EFG30744.1 | hscB | HMPREF9021_01350 | HMPREF9021_00004 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.992 |
EFG30744.1 | iscS | HMPREF9021_01350 | HMPREF9021_01355 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.999 |